|
|
| Seong, H-A. and Ha, H. (2019) Thr55 phosphorylation of p21 by MPK38/MELK ameliorates defects in glucose, lipid, and energy metabolism in diet-induced obese mice. Cell Death Dis. 10:380 |
|
| Seong, H-A., Manoharan, R., and Ha, H. (2018) Smad proteins differentially regulate obesity-induced glucose and lipid abnormalities and inflammation via class-specific control of AMPK-related kinase MPK38/MELK activity. Cell Death Dis. 9:471 |
|
| Manoharan, R., Seong, H-A., and Ha, H. (2018) Dual roles of serine-threonine kinase receptor-associated protein (STRAP) in redox-sensitive signaling pathways related to cancer development. Oxid. Med. Cell. Longev., Vol 2018, article ID 5241524, 9 pages |
|
| Kim MJ, Kim WS, Kim DO, Byun JE, Huy H, Lee SY, Song HY, Park YJ, Kim TD, Yoon SR, Choi EJ, Ha H, Jung H, Choi I. (2017) Macrophage migration inhibitory factor interacts with thioredoxin-interacting protein and induces NF-κB activity. Cell. Signal. 34, 110-120. |
|
| Seong, H-A., Manoharan, R., and Ha, H. (2017) Zinc finger protein ZPR9 functions as an activator of AMPK-related serine/threonine kinase MPK38/MELK involved in ASK1/ TGF-β/p53 signaling pathways. Sci. Rep. 7:42502 |
|
| Seong, H-A., Manoharan, R., and Ha, H. (2016) Coordinate activation of redox-dependent ASK1/TGF-β signaling by a multi-protein complex (MPK38, ASK1, SMADs, ZPR9, and TRX) improves glucose and lipid metabolism in mice. Antioxid. Redox Signal. 24, 434-452. |
|
| Seong, H-A., Manoharan, R., and Ha, H. (2014) A crucial role for the phosphorylation of STRAP at Ser188 by MPK38 in STRAP-dependent cell death through ASK1, TGF-β, p53, and PI3K/PDK1 signaling pathways. Cell Cycle 13, 3357-3374.
|
|
| Kim, S., Park, D-Y., Lee, D., Kim, W., Jeong, Y-H, Lee, J., Chung, S-K., Ha, H., Choi, B-H., and Kim, KT. (2014) Vaccinia-related kinase 2 mediates accumulation of polyglutamine aggregates via negative regulation of the chaperonin TRiC. Mol. Cell. Biol. 34, 643-652.
|
|
| Manoharan, R., Seong, H-A., and Ha, H. (2013) Thioredoxin inhibits MPK38-induced ASK1, TGF-β, and p53 function in a phosphorylation-dependent manner. Free Radical Biology & Medicine 63, 313-324.
|
|
| Seong, H-A., Jung, H., Manoharan, R., and Ha, H. (2012) PDK1 Phosphorylation at Thr354 by Murine Protein Serine/Threonine Kinase 38 Contributes to the Negative Regulation of PDK1 Activity. J. Biol. Chem. 287, 20811-20822.
|
|
|
|
연구논문/저서
